Health & Fitness · Review · Updated 17 October 2026
Calecim Professional reviewPremium stem cell-derived skincare and hair serums built on the PTT-6 ingredient
Good
Brent score, out of 5
Calecim is a high-end, clinic-style skincare line from a Singapore stem cell company, built around one patented ingredient, PTT-6. The science behind the source is real and patented, but the headline results are company-reported, and the prices are steep for small sizes. It suits people who already spend on premium skincare and want to try an exosome-style product; everyone else should start with proven basics.
Price
From US$60 (Recovery Night Complex); serum US$100 for 5 ml
Free option
Paid only
Best for
People already spending on premium anti-aging skincare
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Best for
- People already spending on premium anti-aging skincare
- Clients of aesthetic clinics who use post-treatment products
- Buyers curious about exosome and growth-factor skincare
- Those in the US, UK or Singapore, where shipping is free
Skip it if
- Budget buyers, since a 5 ml serum is US$100
- Anyone who wants independent clinical trials before buying
- People seeking a medical treatment for hair loss or skin disease
Your skin has started to lose bounce. Fine lines stay after you stop smiling, and the drugstore retinol and vitamin C you bought have stopped feeling like enough. Clinic treatments help, but they are expensive and you want something at home that matches that level.
Calecim Professional sells skincare and hair serums based on PTT-6, an ingredient its maker describes as containing more than 3,000 proteins, including growth factors, cytokines and exosomes, from a patented stem cell source. The company behind it, CellResearch Corporation in Singapore, works on umbilical cord lining stem cells.
This review explains what Calecim sells, what it costs in US dollars, what the claims are based on, and who should save their money.
What is Calecim Professional?
Calecim Professional is a cosmeceutical line from Singapore's CellResearch Corporation, a biotech focused on umbilical cord lining stem cells. Its products use PTT-6, which the brand describes as a single active containing over 3,000 proteins, including growth factors, cytokines and exosomes. The range covers a Professional Serum, Multi-Action Cream, Restorative Hydration Cream, Eye Contour Lifting Cream, Recovery Night Complex, a Pigment Solution kit and a 6-week Hair Serum. The site states the products are cosmetics, not intended to diagnose, treat, cure or prevent disease, and not FDA approved.
Pros and cons
What we like
- Single, consistent active ingredient (PTT-6) across the range
- Backed by CellResearch Corporation's patented umbilical cord lining stem cell work
- Free shipping to the US, UK and Singapore with tax absorbed
- Fast delivery: 3-6 working days to the US and UK, 2 to Singapore
- 10% off first order on sign-up and up to 20% off with Auto-Replenish
What could be better
- Very high price per ml (US$100 for 5 ml serum, US$160 for 15 ml eye cream)
- Efficacy figures like a 56% rise in elastin are company-reported, without study details on the site
- Hair Serum costs US$360 for a 6-week program and needs a derma stamp
- Returns terms aren't stated on the main shop pages
Overall
Good
- Formulation4.2
- Evidence3.4
- Value3.4
- Shipping4.2
Key features of Calecim Professional
PTT-6 active ingredient
Every product is built on PTT-6, sourced from what the brand calls a patented stem cell source. Patent filings and a Cordlife press release link PTT-6 to CellResearch's umbilical cord lining stem cell work.
Professional Serum
The 5 ml serum (US$100) carries the highest PTT-6 concentration in the range and targets fine lines and wrinkles.
Multi-Action and Eye creams
Multi-Action Cream (from US$68) aims at collagen and elastin support for skin losing volume. The 15 ml Eye Contour Lifting Cream (US$160) is used morning and night.
Hair Serum program
A 6-week program (6 x 5 ml, US$360) applied with a derma stamp twice a week. The brand reports a 24% increase in hair follicle cell production and a 30x drop in scalp inflammation.
Bundles and Auto-Replenish
Bundles like Eye Contour + Multi-Action Cream start at US$228 with savings up to 15%. Auto-Replenish subscriptions offer up to 20% off.
Shipping coverage
Free shipping with tax absorbed to the US, UK and Singapore, and free shipping with tax charged to many European countries. Other countries pay delivery fees, with international delivery up to 14 working days.
Calecim Professional pricing
Checked 2026-10. Prices can change; confirm on Calecim (CellResearch Corporation, Singapore)’s site.
Recovery Night Complex
From US$60
one-off purchase
- Night treatment with PTT-6
Multi-Action Cream
From US$68
one-off purchase
- Collagen and elastin support
- 20 g starter kit US$85
Professional Serum
US$100
one-off purchase, 5 ml
- Highest PTT-6 concentration
Eye Contour Lifting Cream
US$160
one-off purchase, 15 ml
- AM and PM use
Hair Serum
US$360
6-week program, 6 x 5 ml
- Applied with a derma stamp twice weekly
Watch out: Prices are in USD on the brand's store; countries outside the US, UK, Singapore and parts of Europe pay delivery fees, and the 10% first-order and 20% Auto-Replenish discounts depend on signing up.
See current Calecim Professional pricing →What people use Calecim Professional for
Adding one premium step
Someone with a basic routine of cleanser, sunscreen and moisturiser swaps their moisturiser for the Multi-Action Cream. It is the lowest-risk way to try PTT-6 without buying a full regimen.
Eye area focus
A buyer worried mainly about crow's feet chooses the Eye Contour Lifting Cream. At US$160 for 15 ml, it is a deliberate splurge on one area.
Thinning hair at home
A buyer who already uses a derma stamp tries the 6-week Hair Serum program. Because it is a cosmetic, anyone with ongoing hair loss should talk to a doctor or dermatologist first.
How to get started with Calecim Professional
- 1
Decide on one concern (lines, volume, eyes or hair) and pick a single product
- 2
Sign up on the site for the 10% first-order discount
- 3
Patch-test on a small area before full use
- 4
Use it consistently for several weeks before judging results
- 5
Talk to your doctor or dermatologist if you have a skin condition or hair loss
Calecim Professional alternatives
| Product | Choose it when |
|---|---|
| Calecim Professional 3.9 | People already spending on premium anti-aging skincare |
| SkinMedica TNS Advanced+ Serum | A long-established growth factor serum sold through clinics, for those who prefer a bigger brand. |
| The Ordinary Buffet + Copper Peptides | A low-cost peptide serum for people who want to try anti-aging actives without premium pricing. |
| Prescription retinoids via a doctor | The best-studied option for fine lines; ask your doctor if it suits you. |
Calecim Professional: frequently asked questions
What is PTT-6 in Calecim?+
PTT-6 is Calecim's active ingredient, which the brand says contains over 3,000 proteins, including growth factors, cytokines and exosomes. Patent filings from CellResearch Corporation describe PTT-6 in connection with growing stem cells from umbilical cord lining.
Is Calecim legit?+
Calecim is made by CellResearch Corporation, a Singapore biotech with patents on umbilical cord lining stem cells. The products are sold as cosmetics, not FDA-approved drugs, and the performance figures on the site are company-reported.
Does Calecim Hair Serum work for hair loss?+
The brand reports a 24% increase in hair follicle cell production and a 30x reduction in scalp inflammation, but the site doesn't give study details. It is a cosmetic, so talk to your doctor about hair loss before relying on it.
How much does Calecim cost?+
On the brand's store, Recovery Night Complex starts at US$60, Multi-Action Cream at US$68, the 5 ml Professional Serum is US$100, the 15 ml Eye Contour Lifting Cream is US$160 and the 6-week Hair Serum is US$360.
Does Calecim ship internationally?+
Yes. Shipping is free to the US, UK and Singapore, free with tax charged to many European countries, and paid elsewhere. International orders take up to 14 working days.
Final verdict
Is Calecim Professional worth it?
If you already invest in premium skincare and want to try a stem cell-derived, exosome-style product, Calecim is a focused place to start. Pick one product for your main concern, use the first-order discount, and give it several weeks.
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Reviewed by
Amjid Ali, Founder and editor
Amjid Ali is a Melbourne-based AI and automation lead, author of five books on infrastructure, automation and digital transformation, and a corporate trainer whose courses on n8n, Proxmox, firewalls and ERP have taught thousands of IT professionals.
Last updated 17 October 2026 · How we review
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Calecim Professional 3.9
From US$60 (Recovery Night Complex); serum US$100 for 5 ml